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Domino's Ultimate Pepperoni Pizza, Large 14" Hand Tossed Nutrition Facts

One serving of Domino's Ultimate Pepperoni Pizza, Large 14" Hand Tossed (1 slice (1/8 pizza, 125 g)) has 360 calories, 15g of protein, 34g of carbohydrates (33g net carbs), 18g of fat and 830mg of sodium.

About 17% of its calories come from protein, 38% from carbs and 45% from fat.

How it compares with other specialty pizzas (per slice)

Among 44 items in Specialty Pizzas (per slice), it ranks #16 for fewest calories and #32 for most protein. Showing the closest items by calories.

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Nutrition Facts

Serving: 1 slice (1/8 pizza, 125 g)

Calories360

% Daily Value*

Total Fat 18g
23%
Saturated Fat 8g
40%
Trans Fat 0g
Cholesterol 40mg
13%
Sodium 830mg
36%
Total Carbohydrate 34g
12%
Dietary Fiber 1g
4%
Total Sugars 3g
Protein 15g
30%

* Percent Daily Values are based on a 2,000 calorie diet. Figures are estimates from published restaurant data; actual portions vary by location.

Source: Domino's Nutrition Guide, US (August 2026), checked August 2026.