Domino's Italian Sandwich Nutrition Facts
One serving of Domino's Italian Sandwich (1/2 Sandwich) has 420 calories, 20g of protein, 35g of carbohydrates (35g net carbs), 22g of fat and 1,520mg of sodium.
About 19% of its calories come from protein, 33% from carbs and 47% from fat.
How it compares with other oven-baked sandwiches
Among 5 items in Oven-Baked Sandwiches, it ranks #4 for fewest calories and #3 for most protein.
| Item | Cal | Protein | Carbs | Fat | Sodium |
|---|---|---|---|---|---|
| Buffalo Chicken Sandwich | 420 | 19g | 36g | 22g | 1,250mg |
| Chicken Bacon Ranch Sandwich | 470 | 22g | 35g | 26g | 1,170mg |
| Chicken Parm Sandwich | 410 | 24g | 36g | 19g | 1,030mg |
| Italian Sandwich | 420 | 20g | 35g | 22g | 1,520mg |
| Philly Cheese Steak Sandwich | 370 | 18g | 37g | 17g | 1,200mg |
Related Domino's guides
Nutrition Facts
Serving: 1/2 Sandwich
Calories420
% Daily Value*
- Total Fat 22g
- 28%
- Saturated Fat 9g
- 45%
- Trans Fat 0.5g
- Cholesterol 60mg
- 20%
- Sodium 1,520mg
- 66%
- Total Carbohydrate 35g
- 13%
- Dietary Fiber 0g
- 0%
- Total Sugars 2g
- Protein 20g
- 40%
* Percent Daily Values are based on a 2,000 calorie diet. Figures are estimates from published restaurant data; actual portions vary by location.
Source: Domino's Nutrition Guide, US (August 2026), checked August 2026.